Synthetic chemotherapeutic agents. IV. Synthesis of 3-substituted thiazolo(5,4-f)quinoline derivatives.
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چکیده
منابع مشابه
Synthesis of 1, 3-diaryl Substituted Iodobenzene Derivatives
The synthesis and characterization a new derivatives of 2'-iodo-meta terphenyl from the reaction ofexcess aryl-Grignard and 2, 6- dichloroiodobenzene with quenching of m-terphenyl-2'-magnesiumbromide by iodine is reported. Via the reactions three carbon-carbon bonds are constructed and mterphenylsare obtained in good yields.
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In a search for new bactericidal and fungicidal agents some new piperazine-TV, TV'-bis-substituted derivatives have been prepared and characterized by their elemental analysis, IR, *H N M R , and mass spectral d a t a . T h e ant ibacter ia l and antifungal activities of all p repared c o m p o u n d s have been determined using Gentamycin as s t a n d a r d antibiotic. Some c o m p o u n d s s...
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the synthesis and characterization a new derivatives of 2'-iodo-meta terphenyl from the reaction ofexcess aryl-grignard and 2, 6- dichloroiodobenzene with quenching of m-terphenyl-2'-magnesiumbromide by iodine is reported. via the reactions three carbon-carbon bonds are constructed and mterphenylsare obtained in good yields.
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A number of N-arylmethyl substituted indole derivatives have been synthesized and their effectiveness against ADP and arachidonic acid induced platelet aggregation in human plasma was determined. The desired compounds were synthesized by reacting the appropriate aniline derivative with isatin (or substituted isatin) to form the corresponding imine structures. The so formed compound was then act...
متن کاملSynthesis of N-arylmethyl Substituted Indole Derivatives as New Antiplatelet Aggregation Agents
A number of N-arylmethyl substituted indole derivatives have been synthesized and their effectiveness against ADP and arachidonic acid induced platelet aggregation in human plasma was determined. The desired compounds were synthesized by reacting the appropriate aniline derivative with isatin (or substituted isatin) to form the corresponding imine structures. The so formed compound was then act...
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ژورنال
عنوان ژورنال: Chemical and Pharmaceutical Bulletin
سال: 1976
ISSN: 0009-2363,1347-5223
DOI: 10.1248/cpb.24.1050